Creative Enzymes

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  • City: New York
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Borrelidin

  • CAS No:7184-60-3 Cyclopentanecarboxylicacid,2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-,(1R,2R)-
    Molecular Structure

    Detailed Description

    A macrolide antibiotic isolated from Streptomyces sp. An antiangiogenic (IC50 = 0.8 nM) agent. Bacterial and eukaryal threonyl-tRNA synthetase (THrRS) inhibitor. Induces the collapse of formed capillary tubes in a dose-dependent fashion. In HUVECs, the capillary tube collapsing activity is mediated by the activation of caspases-3 and -8 and induction of apoptosis. Also acts as a CDK inhibitor. More information please visit the website: http://www.creative-enzymes.com/product/Borrelidin_2358.html

  • Borrelidin
  • Borrelidin